WNT11

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq, Jul 2008]

Description

Wnt family member 11

Tissue specificity

Tissue enhanced (adipose tissue)

Predicted location

Intracellular, Secreted to extracellular matrix

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

11 (76186325 - 76210736)

Ensembl ID

ENSG00000085741  (ver. 103.38)

Orthologs

Mouse Wnt11: ENSMUSG00000015957

UniProt

O96014

neXtProt

NX_O96014

Human splice variants
Mouse splice variants

Protein structure