ATP6V0A4

gene product
a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
114 antibodies from 20 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
48 antibodies
Atlas Antibodies
2 antibodies
LifeSpan BioSciences, Inc.
21 antibodies
Novus Biologicals
3 antibodies
Biorbyt
3 antibodies
GeneTex
2 antibodies
Abnova Corporation
2 antibodies
Invitrogen Antibodies
3 antibodies
NovoPro Bioscience Inc.
1 antibody
Aviva Systems Biology
3 antibodies
OriGene
1 antibody
ProSci
1 antibody
MyBioSource
5 antibodies
Boster Biological Technology
1 antibody
RabMAbs
1 antibody
Signalway Antibody LLC
1 antibody
St John's Laboratory
1 antibody
United States Biological
13 antibodies
Creative Diagnostics
1 antibody
Sigma-Aldrich
1 antibody