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Protein structure
OAS2
2'-5'-oligoadenylate synthetase 2This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  19279-1-AP |
20 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 19279-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| LSBio | LS-C789657 |
Monoclonal |
WB
IHC
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| NovoPro Bioscience Inc. | 113460 |
Polyclonal |
WB
EL
ICC
IP
IHC
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| FineTest Biotech | FNab05951 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
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