Tissue expression
Cell line expression
Protein structure
LZTS2
Leucine zipper tumor suppressor 2KIAA1813, LAPSER1
The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Top validated antibodies |
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Proteintech Group | 15677-1-AP | 3 references | Polyclonal |
WB
EL
IHC
|
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GeneTex | GTX31845 | Polyclonal |
WB
EL
ICC
IHC |
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Boster Biological Technology | A07806-1 | Polyclonal |
WB
EL
ICC
IHC |
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antibodies-online | ABIN4332232 | Polyclonal |
WB
EL
ICC
IHC |
||
Atlas Antibodies | HPA044956 | Polyclonal |
WB
ICC
IHC
|
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