TPCN1

Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 [PubMed 10753632]). [supplied by OMIM, Mar 2008]

Description

two pore segment channel 1

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted membrane proteins, Protein evidence (Peptideatlas), Transporters, Voltage-gated ion channels

Chromosome

12:q24.13 (113221050 - 113298585)

Ensembl ID

ENSG00000186815  (ver. 99.38)

Orthologs

Mouse Tpcn1: ENSMUSG00000032741

UniProt

Q9ULQ1

neXtProt

NX_Q9ULQ1

Human splice variants
Mouse splice variants