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LearnBS6777
antibody from Bioworld Technology, Inc
Targeting: BTRC
beta-TrCP1, betaTrCP, bTrCP, bTrCP1, FBXW1A, Fwd1
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS6777 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- BTRC polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human BTRC.
- Description
- ?-TrCP (beta-tranducin repeats containing protein), also designated E3RSIkB or FWD1, and HOS (homologous to Slimb) are F-box proteins that function as substrate recognition subunits of ubiquitin ligases. HOS and ?-TrCP differ in their amino terminal regions, but exhibit high homology within the F-box and WD40 repeat-containing regions. ?-TrCP mediates ubiquitin/proteasome-dependent degradation of CD4 and ubiquitination of various proteins including IkB and ?-catenin. HOS has also been shown to regulate the degradation of IkB and ?-catenin in a similar manner.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot analysis of extracts of Kidney cell line, using BTRC antibody.
