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antibody from antibodies-online
Targeting: BTRC
beta-TrCP1, betaTrCP, bTrCP, bTrCP1, FBXW1A, Fwd1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- ABIN952275 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-beta-Transducin Repeat Containing (BTRC) (AA 24-60), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Affinity chromatography on Protein A
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 24-60, N-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Ubiquitylation of the amino terminus of Myc by SCF(β-TrCP) antagonizes SCF(Fbw7)-mediated turnover.
Plk4 trans-autophosphorylation regulates centriole number by controlling betaTrCP-mediated degradation.
Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.
Role of macrophage oxidative burst in the action of anthrax lethal toxin.
Popov N, Schülein C, Jaenicke LA, Eilers M
Nature cell biology 2010 Oct;12(10):973-81
Nature cell biology 2010 Oct;12(10):973-81
Plk4 trans-autophosphorylation regulates centriole number by controlling betaTrCP-mediated degradation.
Guderian G, Westendorf J, Uldschmid A, Nigg EA
Journal of cell science 2010 Jul 1;123(Pt 13):2163-9
Journal of cell science 2010 Jul 1;123(Pt 13):2163-9
Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.
Inuzuka H, Tseng A, Gao D, Zhai B, Zhang Q, Shaik S, Wan L, Ang XL, Mock C, Yin H, Stommel JM, Gygi S, Lahav G, Asara J, Xiao ZX, Kaelin WG Jr, Harper JW, Wei W
Cancer cell 2010 Aug 9;18(2):147-59
Cancer cell 2010 Aug 9;18(2):147-59
Role of macrophage oxidative burst in the action of anthrax lethal toxin.
Hanna PC, Kruskal BA, Ezekowitz RA, Bloom BR, Collier RJ
Molecular medicine (Cambridge, Mass.) 1994 Nov;1(1):7-18
Molecular medicine (Cambridge, Mass.) 1994 Nov;1(1):7-18
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Supportive validation
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- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Confocal immunofluorescent analysis of BRTC1 Antibody (N-term)(Cat#AP50409PU-N) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
