24743-1-AP

antibody from Proteintech Group

Targeting: ACE ACE1, CD143, DCP1

Provider product page for 24743-1-AP

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [26]
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Validations
Western blot [1]

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Product number: 24743-1-AP - Provider product page
Provider: Proteintech Group
Product name: ACE antibody
Antibody type: Polyclonal
Description: ACE antibody (Cat. #24743-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ACE protein structure - 24743-1-AP shown in red.

Submitted references Candesartan upregulates angiotensin-converting enzyme 2 in kidneys of male animals by decreased ubiquitination.

Wang P, Ren Z, Wang W, Liu M, Jia Y, Zhang M, Xue Y, Zhang C, Xu J, Wang C, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23537

Glycyrrhizic acid restores the downregulated hepatic ACE2 signaling in the attenuation of mouse steatohepatitis.

Zhou L, Chen S, Wei Y, Sun Y, Yang Y, Lin B, Li Y, Wang C
European journal of pharmacology 2024 Mar 15;967:176365

Gastrodin regulates the expression of renin-angiotensin system-SIRT3 and proinflammatory mediators in reactive astrocytes via activated microglia.

Zuo HJ, Ren XQ, Shi JS, Shi HL, Guo K, Wang PX, Zhao M, Li JJ
The European journal of neuroscience 2024 Jul;60(1):3677-3693

Angiotensin-converting enzyme inhibitory peptide IVGFPAYGH protects against liver injury in mice fed a high‑sodium diet by inhibiting the RAS and remodeling gut microbial communities.

Zou L, Yu X, Cai K, Xu B, Chen C, Xiao G
International journal of biological macromolecules 2024 Jan;256(Pt 1):128265

Hyperoxia-induced airflow restriction and Renin-Angiotensin System expression in a bronchopulmonary dysplasia mouse model.

Dowell J, Bice Z, Yan K, Konduri GG
Physiological reports 2024 Jan;12(1):e15895

Panax notoginseng saponin alleviates pulmonary fibrosis in rats by modulating the renin-angiotensin system.

Li H, Wang YG, Chen TF, Gao YH, Song L, Yang YF, Gao Y, Huo W, Zhang GP
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116979

Integrating Proteomics and Transcriptomics Reveals the Potential Pathways of Hippocampal Neuron Apoptosis in Dravet Syndrome Model Mice.

Kong X, Dai G, Zeng Z, Zhang Y, Gu J, Ma T, Wang N, Gu J, Wang Y
International journal of molecular sciences 2024 Apr 18;25(8)

Pea protein hydrolysate reduces blood glucose in high-fat diet and streptozotocin-induced diabetic mice.

Liao W, Cao X, Xia H, Wang S, Chen L, Sun G
Frontiers in nutrition 2023;10:1298046

Celastrol attenuates streptozotocin-induced diabetic cardiomyopathy in mice by inhibiting the ACE / Ang II / AGTR1 signaling pathway.

Zhao X, Huang B, Zhang J, Xiang W, Zhu N
Diabetology & metabolic syndrome 2023 Sep 12;15(1):186

Losartan attenuates acetic acid enema-induced visceral hypersensitivity by inhibiting the ACE1/Ang II/AT1 receptor axis in enteric glial cells.

Sun Y, Liu X, Wang L, Li L, Quan X, Shi H, Wang T, Mei L, Chen Y, Zhang Y, Li J, Meng R, Wang J, Dai F
European journal of pharmacology 2023 May 5;946:175650

Azelaic Acid Regulates the Renin-Angiotensin System and Improves Colitis Based on Network Pharmacology and Experimentation.

Liao Y, Wu X, Luo W, Chen J, Huang Y, Ma K, Zhang C, Wang J, Yang Y, Deng M, Wang X
ACS omega 2023 May 2;8(17):15217-15228

Hybrids of carbonic anhydrase and cyclooxygenase inhibitors attenuate cardiac hypoxic inflammatory injuries.

Zhou W, Wang C, Zhang B, Gou S
European journal of pharmacology 2023 Jul 5;950:175751

Discovery of Efficient Hypoxia-Targeted NO Donor Compounds to Alleviate Hypoxia Cardiac Disease.

Yang W, Zhou W, Gou S
Journal of medicinal chemistry 2023 Dec 14;66(23):15977-15989

Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia.

Wang P, Zhu G, Wu Q, Shen L, Liu D, Wang Z, Wang W, Ren Z, Jia Y, Liu M, Xue Y, Ji D, Hu Y, Yu Y, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22834

TMPRSS2 Expression and Activity Modulation by Sex-Related Hormones in Lung Calu-3 Cells: Impact on Gender-Specific SARS-CoV-2 Infection.

Treppiedi D, Marra G, Di Muro G, Catalano R, Mangili F, Esposito E, Barbieri AM, Arosio M, Mantovani G, Peverelli E
Frontiers in endocrinology 2022;13:862789

TMT-based quantitative N-glycoproteomic analysis reveals glycoprotein protection can improve the quality of frozen bovine sperm.

Wang N, Yang M, He D, Li X, Zhang X, Han B, Liu C, Hai C, Li G, Zhao Y
International journal of biological macromolecules 2022 Oct 1;218:168-180

Sodium butyrate exerts antioxidant stress effects and attenuates Aβ(25-35)-induced cytotoxicity in PC12 cells.

Yuan B, Liu M, Gong Y, Wang Z, Jin X, Xie G, Zhu M, Zhang X, Luo S, Qu Q, Zhu Y, Wang M, Jin Y, Li B, Wang W
Archives of biochemistry and biophysics 2022 Nov 30;731:109448

Non-Invasive Local Acoustic Therapy Ameliorates Diabetic Heart Fibrosis by Suppressing ACE-Mediated Oxidative Stress and Inflammation in Cardiac Fibroblasts.

Weng L, Li L, Zhao K, Xu T, Mao Y, Shu H, Chen X, Chen J, Wu J, Guo X, Tu J, Zhang D, Sun W, Kong X
Cardiovascular drugs and therapy 2022 Jun;36(3):413-424

Non-canonical Wnt/calcium signaling is protective against podocyte injury and glomerulosclerosis.

Zhou D, Wang Y, Gui Y, Fu H, Zhou S, Wang Y, Bastacky SI, Stolz DB, Liu Y
Kidney international 2022 Jul;102(1):96-107

Tissue Renin-Angiotensin System (tRAS) Induce Intervertebral Disc Degeneration by Activating Oxidative Stress and Inflammatory Reaction.

Sun K, Sun X, Sun J, Jiang Y, Lin F, Kong F, Li F, Zhu J, Huan L, Zheng B, Wang Y, Zou W, Gao L, Xu X, Shi J
Oxidative medicine and cellular longevity 2021;2021:3225439

Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects.

Liu X, Deng R, Wei X, Wang Y, Weng J, Lao Y, Lu J, Xiong G, Li S
Bioscience reports 2021 Oct 29;41(10)

H. sinensis mycelium inhibits epithelial-mesenchymal transition by inactivating the midkine pathway in pulmonary fibrosis.

Lu L, Zhu H, Wang H, Liang H, Hou Y, Dou H
Frontiers of medicine 2021 Apr;15(2):313-329

MiR155-5p Inhibits Cell Migration and Oxidative Stress in Vascular Smooth Muscle Cells of Spontaneously Hypertensive Rats.

Wu N, Ye C, Zheng F, Wan GW, Wu LL, Chen Q, Li YH, Kang YM, Zhu GQ
Antioxidants (Basel, Switzerland) 2020 Mar 1;9(3)

Therapeutic effects of higenamine combined with [6]-gingerol on chronic heart failure induced by doxorubicin via ameliorating mitochondrial function.

Wen J, Zhang L, Wang J, Wang J, Wang L, Wang R, Li R, Liu H, Wei S, Li H, Zou W, Zhao Y
Journal of cellular and molecular medicine 2020 Apr;24(7):4036-4050

RhoA-Rho associated kinase signaling leads to renin-angiotensin system imbalance and angiotensin converting enzyme 2 has a protective role in acute pulmonary embolism.

Xu X, Shi L, Ma X, Su H, Ma G, Wu X, Ying K, Zhang R
Thrombosis research 2019 Apr;176:85-94

Network pharmacology-based strategy for predicting active ingredients and potential targets of Yangxinshi tablet for treating heart failure.

Chen L, Cao Y, Zhang H, Lv D, Zhao Y, Liu Y, Ye G, Chai Y
Journal of ethnopharmacology 2018 Jun 12;219:359-368

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The ACE antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ACE. This antibody recognizes human, mouse antigen. The ACE antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 24743-1-AP.pdf

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