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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 344206 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#344206, RRID:AB_11149487
- Product name
- APC anti-human CD143 (Angiotensin-converting enzyme)
- Antibody type
- Monoclonal
- Antigen
- CD143
- Description
- CD143 (ACE, kininase II, peptidyl dipeptidase 1, peptidase P, carboxycathepsin) is a 171 kD, type I, single chain transmembranal metallopeptidase, whose cofactor is zinc. Its main targets are angiotensin I and bradykinin, acting as a blood pressure regulator. CD143 is expressed in endothelial cells; varying amounts of CD143 have been reported in different epithelial cells. The activation of macrophages and histiocytes induces the expression of this molecule.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- GM-CSF-stimulated human peripheral blood mononuclear cells (day-3) were stained with CD143 (clone 5-369) APC (filled histogram) or mouse IgG1, κ APC isotype control (open histogram). Data shown was gated on CD14+ cell population.
- Conjugate
- Red dye
