CTSC

gene product
DPP1, PALS, PLS
This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. [provided by RefSeq, Nov 2015]
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265 antibodies from 27 providers.

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Novus Biologicals
7 antibodies
R&D Systems
3 antibodies
OriGene
5 antibodies
LifeSpan BioSciences, Inc.
62 antibodies
antibodies-online
97 antibodies
Biorbyt
21 antibodies
Atlas Antibodies
2 antibodies
Invitrogen Antibodies
6 antibodies
Aviva Systems Biology
3 antibodies
GeneTex
1 antibody
St John's Laboratory
4 antibodies
Antibodies.com
1 antibody
Boster Biological Technology
1 antibody
Acris Antibodies GmbH
1 antibody
NSJ Bioreagents
1 antibody
Abnova Corporation
4 antibodies
MyBioSource
11 antibodies
Bioworld Technology, Inc
2 antibodies
Creative Biolabs
4 antibodies
Abgent
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
ProSci
1 antibody
Creative Diagnostics
3 antibodies
Everest Biotech
1 antibody
United States Biological
3 antibodies
Sigma-Aldrich
2 antibodies