Tissue expression
Cell line expression
Protein structure

CTSC

Cathepsin C
DPP1, PALS, PLS 
This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. [provided by RefSeq, Nov 2015]
More gene data

All Antibodies

 

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335 antibodies from 31 providers.

Antibody properties

Applications

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
7 antibodies
R&D Systems
3 antibodies
OriGene
5 antibodies
Biorbyt
64 antibodies
NSJ Bioreagents
2 antibodies
Cusabio Biotech Co., Ltd
7 antibodies
Everest Biotech
1 antibody
FineTest Biotech
1 antibody
antibodies-online
97 antibodies
Invitrogen Antibodies
9 antibodies
Atlas Antibodies
2 antibodies
Aviva Systems Biology
3 antibodies
Boster Biological Technology
2 antibodies
GeneTex
1 antibody
St John's Laboratory
3 antibodies
Antibodies.com
1 antibody
Acris Antibodies GmbH
1 antibody
Abnova Corporation
4 antibodies
MyBioSource
11 antibodies
Bioworld Technology, Inc
2 antibodies
Abgent
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Abbexa
11 antibodies
ProSci
1 antibody
Creative Diagnostics
3 antibodies
Creative Biolabs
4 antibodies
Leading Biology
3 antibodies
United States Biological
3 antibodies
MilliporeSigma / Merck KGaA
3 antibodies