Tissue expression
Cell line expression
Protein structure
TFEC
Transcription factor ECbHLHe34, TCFEC, TFECL
This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Top validated antibodies |
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Invitrogen Antibodies | 13547-1-AP | Polyclonal |
WB
IP
IHC
OA |
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Proteintech Group | 13547-1-AP | Polyclonal |
WB
EL
IP
IHC |
||
NovoPro Bioscience Inc. | 116010 | Polyclonal |
WB
EL
IP
IHC |
||
FineTest Biotech | FNab08628 | Polyclonal |
WB
EL
IP
IHC |
||
Novus Biologicals | NB100-1031 | 2 references | Polyclonal |
WB
EL |
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