Tissue expression
Cell line expression
Protein structure
TFEC
Transcription factor ECbHLHe34, TCFEC, TFECL
This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Top validated antibodies |
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| Invitrogen Antibodies | Polyclonal |
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| Proteintech Group | Polyclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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| FineTest Biotech | Polyclonal |
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| Novus Biologicals | 2 references | Polyclonal |
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