Tissue expression
Cell line expression
Protein structure
BCL7A
BAF chromatin remodeling complex subunit BCL7ABCL7
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals | 1 references | Polyclonal |
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| St John's Laboratory | Polyclonal |
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| Everest Biotech | Polyclonal |
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| Atlas Antibodies | 5 references | Polyclonal |
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| Antibodies.com | Polyclonal |
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