orb67145

antibody from Biorbyt

Targeting: TSC1 hamartin, KIAA0243, LAM, TSC

Western blot (Data presented on provider website)

Antibody Data

Product number

orb67145

Provider

Biorbyt

Product name

TSC1 antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal to TSC1.Tuberous sclerosis 1 protein (TSC1) is a peripheral membrane protein. In complex with TSC2, TSC1inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 bynegatively regulating mTORC1 signaling. It seems not to be required for TSC2 GAP activity towardsRHEB. It is implicated as a tumor suppressor. TSC1 is involved in microtubule-mediated proteintransport, but this seems to be due to unregulated mTOR signaling. Defects in TSC1 are the cause oftuberous sclerosis type 1 (TSC1) and may be the cause of focal cortical dysplasia of Taylor ballooncell type (FCDBC).

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Vial size

100 ul

Storage

-20°C