orb106930

antibody from Biorbyt

Targeting: TSC1 hamartin, KIAA0243, LAM, TSC

Western blot (Data presented on provider website)

Antibody Data

Product number

orb106930

Provider

Biorbyt

Product name

TSC1 antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Rabbit polyclonal to TSC1. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antibody clone number

RB42204

Vial size

80 ul