orb106930

antibody from Biorbyt
Targeting: TSC1 hamartin, KIAA0243, LAM, TSC
Provider product page for orb106930
Western blot

Antibody data

Product number
orb106930 - Provider product page
Provider
Biorbyt
Product name
TSC1 antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide
Description
Rabbit polyclonal to TSC1. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antibody clone number
RB42204
Vial size
80 ul
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
TSC1 protein structure - orb106930 shown in red.