ABIN185619

antibody from antibodies-online

Targeting: TSC1 hamartin, KIAA0243, LAM, TSC

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN185619

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN185619, RRID:AB_10782831

Product name

anti-Tuberous Sclerosis 1 (TSC1) (C-Term) antibody

Antibody type

Polyclonal

Description

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Reactivity

Human

Host

Goat

Epitope

C-Term

Vial size

100 μg

Storage

Aliquot and store at -20°C.

Handling

Minimize freezing and thawing.

References

Submitted references

Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors.

Ballif BA, Roux PP, Gerber SA, MacKeigan JP, Blenis J, Gygi SP
Proceedings of the National Academy of Sciences of the United States of America 2005 Jan 18;102(3):667-72

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Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation.

Chan JA, Zhang H, Roberts PS, Jozwiak S, Wieslawa G, Lewin-Kowalik J, Kotulska K, Kwiatkowski DJ
Journal of neuropathology and experimental neurology 2004 Dec;63(12):1236-42

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TSC2 modulates actin cytoskeleton and focal adhesion through TSC1-binding domain and the Rac1 GTPase.

Goncharova E, Goncharov D, Noonan D, Krymskaya VP
The Journal of cell biology 2004 Dec 20;167(6):1171-82