Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN358402 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tuberous Sclerosis 1 (TSC1) (pSer505) antibody
- Antibody type
- Polyclonal
- Description
- Affinity purification in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer505
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Hamartin and tuberin immunohistochemical expression in cutaneous fibroepithelial polyps.
Genotype and psychological phenotype in tuberous sclerosis.
Pam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complex.
Tuberin and hamartin expression is reduced in the majority of subependymal giant cell astrocytomas in tuberous sclerosis complex consistent with a two-hit model of pathogenesis.
Cell cycle-regulated phosphorylation of hamartin, the product of the tuberous sclerosis complex 1 gene, by cyclin-dependent kinase 1/cyclin B.
Wu J, Khalil FK, Keehn CA, Saeed S, Morgan MB
Journal of cutaneous pathology 2004 May;31(5):383-7
Journal of cutaneous pathology 2004 May;31(5):383-7
Genotype and psychological phenotype in tuberous sclerosis.
Lewis JC, Thomas HV, Murphy KC, Sampson JR
Journal of medical genetics 2004 Mar;41(3):203-7
Journal of medical genetics 2004 Mar;41(3):203-7
Pam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complex.
Murthy V, Han S, Beauchamp RL, Smith N, Haddad LA, Ito N, Ramesh V
The Journal of biological chemistry 2004 Jan 9;279(2):1351-8
The Journal of biological chemistry 2004 Jan 9;279(2):1351-8
Tuberin and hamartin expression is reduced in the majority of subependymal giant cell astrocytomas in tuberous sclerosis complex consistent with a two-hit model of pathogenesis.
Jóźwiak S, Kwiatkowski D, Kotulska K, Larysz-Brysz M, Lewin-Kowalik J, Grajkowska W, Roszkowski M
Journal of child neurology 2004 Feb;19(2):102-6
Journal of child neurology 2004 Feb;19(2):102-6
Cell cycle-regulated phosphorylation of hamartin, the product of the tuberous sclerosis complex 1 gene, by cyclin-dependent kinase 1/cyclin B.
Astrinidis A, Senapedis W, Coleman TR, Henske EP
The Journal of biological chemistry 2003 Dec 19;278(51):51372-9
The Journal of biological chemistry 2003 Dec 19;278(51):51372-9
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