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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 20988-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20988-1-AP, RRID:AB_10950398
- Product name
- Hamartin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Hamartin antibody (Cat. #20988-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Genetic Ablation of LAT1 Inhibits Growth of Liver Cancer Cells and Downregulates mTORC1 Signaling.
Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate.
UBE2S exerts oncogenic activities in urinary bladder cancer by ubiquitinating TSC1.
mTORC1 promotes mineralization via p53 pathway.
Combination therapy with ropivacaine-loaded liposomes and nutrient deprivation for simultaneous cancer therapy and cancer pain relief.
miR-301a Suppression within Fibroblasts Limits the Progression of Fibrosis through the TSC1/mTOR Pathway.
Synthetic lethality by targeting the RUVBL1/2-TTT complex in mTORC1-hyperactive cancer cells.
Activation of mTORC1 in fibroblasts accelerates wound healing and induces fibrosis in mice.
Tuberous sclerosis complex exhibits a new renal cystogenic mechanism.
Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins.
Kim SY, Ong Q, Liao Y, Ding Z, Tan AQL, Lim LTR, Tan HM, Lim SL, Lee QY, Han W
International journal of molecular sciences 2023 May 24;24(11)
International journal of molecular sciences 2023 May 24;24(11)
Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate.
Ou M, Cho HY, Fu J, Thein TZ, Wang W, Swenson SD, Minea RO, Stathopoulos A, Schönthal AH, Hofman FM, Tang L, Chen TC
Autophagy 2023 Dec;19(12):3169-3188
Autophagy 2023 Dec;19(12):3169-3188
UBE2S exerts oncogenic activities in urinary bladder cancer by ubiquitinating TSC1.
Tang H, Fang T, Ji M, Wang JP, Song LL, Zhang QY, Wu JS
Biochemical and biophysical research communications 2021 Nov 12;578:7-14
Biochemical and biophysical research communications 2021 Nov 12;578:7-14
mTORC1 promotes mineralization via p53 pathway.
Luo X, Yin J, Miao S, Feng W, Ning T, Xu S, Huang S, Zhang S, Liao Y, Hao C, Wu B, Ma D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21325
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21325
Combination therapy with ropivacaine-loaded liposomes and nutrient deprivation for simultaneous cancer therapy and cancer pain relief.
Zhang J, Zhu S, Tan Q, Cheng D, Dai Q, Yang Z, Zhang L, Li F, Zuo Y, Dai W, Chen L, Gu E, Xu G, Wei Z, Cao Y, Liu X
Theranostics 2020;10(11):4885-4899
Theranostics 2020;10(11):4885-4899
miR-301a Suppression within Fibroblasts Limits the Progression of Fibrosis through the TSC1/mTOR Pathway.
Wang J, Li X, Zhong M, Wang Y, Zou L, Wang M, Gong X, Wang X, Zhou C, Ma X, Liu M
Molecular therapy. Nucleic acids 2020 Sep 4;21:217-228
Molecular therapy. Nucleic acids 2020 Sep 4;21:217-228
Synthetic lethality by targeting the RUVBL1/2-TTT complex in mTORC1-hyperactive cancer cells.
Shin SH, Lee JS, Zhang JM, Choi S, Boskovic ZV, Zhao R, Song M, Wang R, Tian J, Lee MH, Kim JH, Jeong M, Lee JH, Petukhov M, Lee SW, Kim SG, Zou L, Byun S
Science advances 2020 Jul;6(31):eaay9131
Science advances 2020 Jul;6(31):eaay9131
Activation of mTORC1 in fibroblasts accelerates wound healing and induces fibrosis in mice.
Hu X, Zhang H, Li X, Li Y, Chen Z
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2020 Jan;28(1):6-15
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2020 Jan;28(1):6-15
Tuberous sclerosis complex exhibits a new renal cystogenic mechanism.
Bissler JJ, Zadjali F, Bridges D, Astrinidis A, Barone S, Yao Y, Redd JR, Siroky BJ, Wang Y, Finley JT, Rusiniak ME, Baumann H, Zahedi K, Gross KW, Soleimani M
Physiological reports 2019 Jan;7(2):e13983
Physiological reports 2019 Jan;7(2):e13983
Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins.
Qin Z, Zheng H, Zhou L, Ou Y, Huang B, Yan B, Qin Z, Yang C, Su Y, Bai X, Guo J, Lin J
Scientific reports 2016 Jan 22;6:19587
Scientific reports 2016 Jan 22;6:19587
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 20988-1-AP(hamartin antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The hamartin antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human hamartin. This antibody recognizes human,mouse,rat antigen. The hamartin antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 20988-1-AP(hamartin antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 20988-1-AP(hamartin antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
