Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [2]
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Validation data
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- Product number
- NB100-2821 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-2821, RRID:AB_2209794
- Product name
- Goat Polyclonal TSC1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. This antibody is expected to recognise isoform 1 (NP_000359.1) only.
- Reactivity
- Human
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation.
Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation.
The TSC1 gene product, hamartin, negatively regulates cell proliferation.
The TSC1 gene product, hamartin, negatively regulates cell proliferation.
Chan JA, Zhang H, Roberts PS, Jozwiak S, Wieslawa G, Lewin-Kowalik J, Kotulska K, Kwiatkowski DJ
Journal of neuropathology and experimental neurology 2004 Dec;63(12):1236-42
Journal of neuropathology and experimental neurology 2004 Dec;63(12):1236-42
Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation.
Chan JA, Zhang H, Roberts PS, Jozwiak S, Wieslawa G, Lewin-Kowalik J, Kotulska K, Kwiatkowski DJ
Journal of neuropathology and experimental neurology 2004 Dec;63(12):1236-42
Journal of neuropathology and experimental neurology 2004 Dec;63(12):1236-42
The TSC1 gene product, hamartin, negatively regulates cell proliferation.
Miloloza A, Rosner M, Nellist M, Halley D, Bernaschek G, Hengstschläger M
Human molecular genetics 2000 Jul 22;9(12):1721-7
Human molecular genetics 2000 Jul 22;9(12):1721-7
The TSC1 gene product, hamartin, negatively regulates cell proliferation.
Miloloza A, Rosner M, Nellist M, Halley D, Bernaschek G, Hengstschläger M
Human molecular genetics 2000 Jul 22;9(12):1721-7
Human molecular genetics 2000 Jul 22;9(12):1721-7
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TSC1 Antibody [NB100-2821] - Staining of Human Brain lysate (35 ug protein in RIPA buffer). Antibody at 0.1 ug/mL. Detected by chemiluminescence.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TSC1 Antibody [NB100-2821] - HEK293 overexpressing Human TSC1 and probed with (mock transfection in first lane).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TSC1 Antibody [NB100-2821] - Staining of paraffin embedded Human Uterus. Antibody at 3.75 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TSC1 Antibody [NB100-2821] - Staining of paraffin embedded Human Liver. Antibody at 3.75 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.