20540-1-AP

antibody from Proteintech Group

Targeting: AXIN2 DKFZp781B0869, MGC126582

Provider product page for 20540-1-AP

Western blot

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [19]
Comments [0]
Validations
Western blot [1]

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Product number: 20540-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#20540-1-AP, RRID:AB_10694569
Product name: AXIN2 antibody
Antibody type: Polyclonal
Description: KD/KO validated AXIN2 antibody (Cat. #20540-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

AXIN2 protein structure - 20540-1-AP shown in red.

Submitted references Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.

Ma Y, Zhang P, Zhang Q, Wang X, Miao Q, Lyu X, Cui B, Ma H
Oncology letters 2021 Oct;22(4):688

TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.

Zhou C, Liang Y, Zhou L, Yan Y, Liu N, Zhang R, Huang Y, Wang M, Tang Y, Ali DW, Wang Y, Michalak M, Chen XZ, Tang J
Autophagy 2021 Oct;17(10):3175-3195

An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development.

Wang R, Liu J, Li K, Yang G, Chen S, Wu J, Xie X, Ren H, Pang Y
Journal of experimental & clinical cancer research : CR 2021 Oct 13;40(1):318

Ultrathin 2D Titanium Carbide MXene (Ti₃ C₂ T_x ) Nanoflakes Activate WNT/HIF-1α-Mediated Metabolism Reprogramming for Periodontal Regeneration.

Cui D, Kong N, Ding L, Guo Y, Yang W, Yan F
Advanced healthcare materials 2021 Nov;10(22):e2101215

AXIN2 Reduces the Survival of Porcine Induced Pluripotent Stem Cells (piPSCs).

Zhang R, Yu S, Shen Q, Zhao W, Zhang J, Wu X, Zhu Z, Wu X, Li N, Peng S, Hua J
International journal of molecular sciences 2021 Nov 30;22(23)

Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness.

Xie X, Chen J, Wo D, Ma E, Ning Y, Peng J, Zhu W, Ren DN
Journal of ethnopharmacology 2021 Nov 15;280:114449

TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.

Zhang X, Luo Y, Li Q
OncoTargets and therapy 2020;13:5819-5830

Targeted inhibition of KDM6 histone demethylases eradicates tumor-initiating cells via enhancer reprogramming in colorectal cancer.

Zhang J, Ying Y, Li M, Wang M, Huang X, Jia M, Zeng J, Ma C, Zhang Y, Li C, Wang X, Shu XS
Theranostics 2020;10(22):10016-10030

circ5615 functions as a ceRNA to promote colorectal cancer progression by upregulating TNKS.

Ma Z, Han C, Xia W, Wang S, Li X, Fang P, Yin R, Xu L, Yang L
Cell death & disease 2020 May 11;11(5):356

[PARP10 Influences the Proliferation of Colorectal Carcinoma Cells, a Preliminary Study].

Wu CF, Xiao M, Wang YL, Threadgill MD, Li M, Tang Y, Lin X, Yang L, Li QS, Li X
Molekuliarnaia biologiia 2020 Mar-Apr;54(2):252-261

TRIB3 confers glioma cell stemness via interacting with β-catenin.

Lu Y, Li L, Chen L, Gao Y, Chen X, Cao Y
Environmental toxicology 2020 Jun;35(6):697-706

LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.

Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J
Molecular cancer 2020 Jul 29;19(1):118

Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.

Wang B, Ye Q, Zou C
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507

Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.

Liao X, Song G, Xu Z, Bu Y, Chang F, Jia F, Xiao X, Ren X, Zhang M, Jia Q
BMC cancer 2020 Jan 13;20(1):31

Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress.

Zong Y, Zhang CS, Li M, Wang W, Wang Z, Hawley SA, Ma T, Feng JW, Tian X, Qi Q, Wu YQ, Zhang C, Ye Z, Lin SY, Piao HL, Hardie DG, Lin SC
Cell research 2019 Jun;29(6):460-473

MIR17HG-miR-18a/19a axis, regulated by interferon regulatory factor-1, promotes gastric cancer metastasis via Wnt/β-catenin signalling.

Yuan J, Tan L, Yin Z, Zhu W, Tao K, Wang G, Shi W, Gao J
Cell death & disease 2019 Jun 11;10(6):454

Design, synthesis and biological evaluation of benzoylacrylic acid shikonin ester derivatives as irreversible dual inhibitors of tubulin and EGFR.

Sun WX, Han HW, Yang MK, Wen ZL, Wang YS, Fu JY, Lu YT, Wang MY, Bao JX, Lu GH, Qi JL, Wang XM, Lin HY, Yang YH
Bioorganic & medicinal chemistry 2019 Dec 1;27(23):115153

LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.

Zhu P, Wu J, Wang Y, Zhu X, Lu T, Liu B, He L, Ye B, Wang S, Meng S, Fan D, Wang J, Yang L, Qin X, Du Y, Li C, He L, Ren W, Wu X, Tian Y, Fan Z
Nature cell biology 2018 Oct;20(10):1134-1144

Secreted AGR2 promotes invasion of colorectal cancer cells via Wnt11-mediated non-canonical Wnt signaling.

Tian S, Hu J, Tao K, Wang J, Chu Y, Li J, Liu Z, Ding X, Xu L, Li Q, Cai M, Gao J, Shuai X, Wang G, Wang L, Wang Z
Experimental cell research 2018 Mar 15;364(2):198-207

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The AXIN2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human AXIN2. This antibody recognizes human, mouse, rat antigen. The AXIN2 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 20540-1-AP.pdf

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