Tissue expression
Cell line expression

AXIN2

gene product
DKFZp781B0869, MGC126582 
The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair. [provided by RefSeq, Jul 2008]
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435 antibodies from 38 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Novus Biologicals
6 antibodies
Invitrogen Antibodies
12 antibodies
GeneTex
5 antibodies
antibodies-online
89 antibodies
Biorbyt
57 antibodies
Boster Biological Technology
3 antibodies
LifeSpan BioSciences, Inc.
84 antibodies
NovoPro Bioscience Inc.
5 antibodies
Abgent
3 antibodies
OriGene
4 antibodies
NSJ Bioreagents
1 antibody
Cell Signaling Technology, Inc
2 antibodies
Bioworld Technology, Inc
1 antibody
Cusabio Biotech Co., Ltd
7 antibodies
St John's Laboratory
9 antibodies
Aviva Systems Biology
3 antibodies
Affinity Biosciences
1 antibody
HUABIO Research
1 antibody
ProSci
1 antibody
FabGennix
3 antibodies
Abnova Corporation
3 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Acris Antibodies GmbH
2 antibodies
MyBioSource
4 antibodies
RabMAbs
2 antibodies
R&D Systems
1 antibody
United States Biological
49 antibodies
Abbexa
36 antibodies
Abiocode, Inc.
3 antibodies
Creative Diagnostics
4 antibodies
Creative Biolabs
7 antibodies
EMD Millipore
3 antibodies
RayBiotech, Inc.
2 antibodies
Abbiotec
1 antibody
MilliporeSigma / Merck KGaA
2 antibodies
Rockland Immunochemicals, Inc.
1 antibody