DPABH-07144

antibody from Creative Diagnostics

Targeting: PDHB PDHE1B

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DPABH-07144

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-07144, RRID:AB_2510024

Product name

Rabbit Anti-Human PDHB Polyclonal Antibody

Antibody type

Polyclonal

Description

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _L

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C. Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.