ZCCHC8

gene product
DKFZp434E2220
This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. [provided by RefSeq, Apr 2017]
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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
2 antibodies
antibodies-online
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Atlas Antibodies
2 antibodies
Bethyl Laboratories
3 antibodies
NovoPro Bioscience Inc.
1 antibody
Invitrogen Antibodies
3 antibodies
Abnova Corporation
3 antibodies
LifeSpan BioSciences, Inc.
23 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Biorbyt
7 antibodies
Proteintech Group
1 antibody
Aviva Systems Biology
1 antibody
OriGene
1 antibody
St John's Laboratory
2 antibodies
Boster Biological Technology
1 antibody
Creative Diagnostics
3 antibodies
Creative Biolabs
2 antibodies
United States Biological
14 antibodies
MyBioSource
1 antibody
ProSci
1 antibody