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- Antigen structure
- References [14]
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- Product number
- 21298-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21298-1-AP, RRID:AB_10733102
- Product name
- Kv4.2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Kv4.2 antibody (Cat. #21298-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Synaptic and intrinsic membrane defects disrupt early neural network dynamics in Down syndrome.
NMDA-Type Glutamate Receptor Activation Promotes Ischemic Arrhythmias by Targeting the AKT1-TBX3-Nav1.5 Axis.
Metformin alleviates hyperkalemia-induced arrhythmia and cardiac injury in mice through decreasing SK2 and intracellular Ca(2).
Potassium ion channel modulation at cancer-neural interface enhances neuronal excitability in epileptogenic glioblastoma multiforme.
Fraxinellone protects against cardiac injury and decreases ventricular fibrillation susceptibility during myocardial ischemia-reperfusion.
Constructing a novel prognostic model for triple-negative breast cancer based on genes associated with vasculogenic mimicry.
Environmental Enrichment Improves the Recognition Memory in Adult Mice Following Social Isolation via Downregulation of Kv4.2 Potassium Channels.
Age-Dependent Regulation of Dendritic Spine Density and Protein Expression in Mir324 KO Mice.
Estradiol- and Progesterone-Associated Changes in microRNA-Induced Silencing and Reduced Antiseizure Efficacy of an Antagomir in Female Mice.
Mir324 knockout regulates the structure of dendritic spines and impairs hippocampal long-term potentiation.
Age-dependent regulation of dendritic spine density and protein expression in Mir324 KO mice.
Indoxyl sulfate reduces Ito,f by activating ROS/MAPK and NF-κB signaling pathways.
Pinocembrin alleviates the susceptibility to atrial fibrillation in isoproterenol-induced rats.
MicroRNA inhibition upregulates hippocampal A-type potassium current and reduces seizure frequency in a mouse model of epilepsy.
Hannan SB, Alić I, Murray A, Kwon J, Mortensen M, Kang HJ, Plećaš A, Goh PA, O'Brien NL, Naud R, Nižetić D, Smart TG
Nature communications 2026 Jan 22;17(1):1287
Nature communications 2026 Jan 22;17(1):1287
NMDA-Type Glutamate Receptor Activation Promotes Ischemic Arrhythmias by Targeting the AKT1-TBX3-Nav1.5 Axis.
He Y, Zhang H, Zhang Q, Sun Z, Sun X, Xia L, Zheng L, Wang L
Acta physiologica (Oxford, England) 2025 Sep;241(9):e70085
Acta physiologica (Oxford, England) 2025 Sep;241(9):e70085
Metformin alleviates hyperkalemia-induced arrhythmia and cardiac injury in mice through decreasing SK2 and intracellular Ca(2).
Cui J, Adu-Amankwaah J, Song H, Wang R, Song N, Liu K, Yang D, Du M, Kong D, Wang S, Mi S, Tan R
Life sciences 2025 Sep 1;376:123740
Life sciences 2025 Sep 1;376:123740
Potassium ion channel modulation at cancer-neural interface enhances neuronal excitability in epileptogenic glioblastoma multiforme.
Zhang Y, Duan W, Chen L, Chen J, Xu W, Fan Q, Li S, Liu Y, Wang S, He Q, Li X, Huang Y, Peng H, Zhao J, Zhang Q, Qiu Z, Shao Z, Zhang B, Wang Y, Tian Y, Shu Y, Qin Z, Chi Y
Neuron 2025 Jan 22;113(2):225-243.e10
Neuron 2025 Jan 22;113(2):225-243.e10
Fraxinellone protects against cardiac injury and decreases ventricular fibrillation susceptibility during myocardial ischemia-reperfusion.
Huang R, Zhong X, Tang P, Huang Q, Chen X, Ye L, Luo D, Yang Y, Lei Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117560
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117560
Constructing a novel prognostic model for triple-negative breast cancer based on genes associated with vasculogenic mimicry.
Ren Y, Feng L, Tan Z, Zhou F, Liu S
Aging 2024 May 8;16(9):8086-8109
Aging 2024 May 8;16(9):8086-8109
Environmental Enrichment Improves the Recognition Memory in Adult Mice Following Social Isolation via Downregulation of Kv4.2 Potassium Channels.
Shang Q, Dong YB, Xu L, Yang JH, Li JW, Yu WY, Sun J, Gao X, Huang Y, Zhang XQ
Molecular neurobiology 2024 Jun;61(6):3742-3752
Molecular neurobiology 2024 Jun;61(6):3742-3752
Age-Dependent Regulation of Dendritic Spine Density and Protein Expression in Mir324 KO Mice.
Parkins EV, Burwinkel JM, Ranatunga R, Yaser S, Hu YC, Tiwari D, Gross C
Journal of molecular neuroscience : MN 2023 Oct;73(9-10):818-830
Journal of molecular neuroscience : MN 2023 Oct;73(9-10):818-830
Estradiol- and Progesterone-Associated Changes in microRNA-Induced Silencing and Reduced Antiseizure Efficacy of an Antagomir in Female Mice.
Tiwari D, Rajathi V, Rymer JK, Beasley LN, McGann AM, Bunk AT, Parkins EV, Rice MF, Smith KE, Ritter DM, White AR, Doerning CM, Gross C
eNeuro 2023 Jul;10(7)
eNeuro 2023 Jul;10(7)
Mir324 knockout regulates the structure of dendritic spines and impairs hippocampal long-term potentiation.
Parkins EV, Brager DH, Rymer JK, Burwinkel JM, Rojas D, Tiwari D, Hu YC, Gross C
Scientific reports 2023 Dec 8;13(1):21919
Scientific reports 2023 Dec 8;13(1):21919
Age-dependent regulation of dendritic spine density and protein expression in Mir324 KO mice.
Parkins EV, Burwinkel JM, Ranatunga R, Yaser S, Hu YC, Tiwari D, Gross C
Research square 2023 Aug 7;
Research square 2023 Aug 7;
Indoxyl sulfate reduces Ito,f by activating ROS/MAPK and NF-κB signaling pathways.
Yang J, Li H, Zhang C, Zhou Y
JCI insight 2022 Feb 8;7(3)
JCI insight 2022 Feb 8;7(3)
Pinocembrin alleviates the susceptibility to atrial fibrillation in isoproterenol-induced rats.
Liu Z, Chen X, Ye T, Wan W, Yu Y, Zhang C, Yang B
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):33-40
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):33-40
MicroRNA inhibition upregulates hippocampal A-type potassium current and reduces seizure frequency in a mouse model of epilepsy.
Tiwari D, Brager DH, Rymer JK, Bunk AT, White AR, Elsayed NA, Krzeski JC, Snider A, Schroeder Carter LM, Danzer SC, Gross C
Neurobiology of disease 2019 Oct;130:104508
Neurobiology of disease 2019 Oct;130:104508
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Kv4.2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Kv4.2. This antibody recognizes human,mouse,rat antigen. The Kv4.2 antibody has been validated for the following applications: ELISA, WB analysis.
