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SPHK2
Sphingosine kinase 2This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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| Proteintech Group |  17096-1-AP |
38 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Novus Biologicals | NBP2-52567 |
1 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| Invitrogen Antibodies | 17096-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| LSBio | LS-C118372 |
Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN4355668 |
Monoclonal |
EL
ICC
IHC
FC
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