Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [5]
- ELISA [1]
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- Product number
- ABIN393738 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 1-316) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-316
- Isotype
- IgG
- Antibody clone number
- 3H12-C11
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Sorafenib with doxorubicin augments cytotoxicity to renal cell cancer through PERK inhibition.
Viral host-range factor C7 or K1 is essential for modified vaccinia virus Ankara late gene expression in human and murine cells, irrespective of their capacity to inhibit protein kinase R-mediated phosphorylation of eukaryotic translation initiation factor 2alpha.
Hsp90 mediates activation of the heme regulated eIF-2 alpha kinase during oxidative stress.
OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress.
Conformational characterization of human eukaryotic initiation factor 2alpha: a single tryptophan protein.
Shiota M, Eto M, Yokomizo A, Tada Y, Takeuchi A, Masubuchi D, Inokuchi J, Tatsugami K, Kuroiwa K, Uchiumi T, Seki N, Naito S
International journal of oncology 2010 Jun;36(6):1521-31
International journal of oncology 2010 Jun;36(6):1521-31
Viral host-range factor C7 or K1 is essential for modified vaccinia virus Ankara late gene expression in human and murine cells, irrespective of their capacity to inhibit protein kinase R-mediated phosphorylation of eukaryotic translation initiation factor 2alpha.
Backes S, Sperling KM, Zwilling J, Gasteiger G, Ludwig H, Kremmer E, Schwantes A, Staib C, Sutter G
The Journal of general virology 2010 Feb;91(Pt 2):470-82
The Journal of general virology 2010 Feb;91(Pt 2):470-82
Hsp90 mediates activation of the heme regulated eIF-2 alpha kinase during oxidative stress.
Kulkarni AP, Mittal SP, Devasagayam TP, Pal JK
Indian journal of biochemistry & biophysics 2010 Apr;47(2):67-74
Indian journal of biochemistry & biophysics 2010 Apr;47(2):67-74
OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress.
Wehner KA, Schütz S, Sarnow P
Molecular and cellular biology 2010 Apr;30(8):2006-16
Molecular and cellular biology 2010 Apr;30(8):2006-16
Conformational characterization of human eukaryotic initiation factor 2alpha: a single tryptophan protein.
Sreejith RK, Yadav VN, Varshney NK, Berwal SK, Suresh CG, Gaikwad SM, Pal JK
Biochemical and biophysical research communications 2009 Dec 11;390(2):273-9
Biochemical and biophysical research communications 2009 Dec 11;390(2):273-9
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- Experimental details
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA