12-8828-42

antibody from Invitrogen Antibodies
Targeting: GNLY D2S69E, LAG-2, LAG2, NKG5, TLA519
Provider product page for 12-8828-42

Antibody data

Product number
12-8828-42 - Provider product page
Provider
Invitrogen Antibodies
Product name
Granulysin Monoclonal Antibody (eBioDH2 (DH2)), PE, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The eBioDH2 monoclonal antibody reacts with human granulysin, a protein involved in the cytolytic pathway. Granulysin is a member of the saposin-like protein (SAPLIP) family. Two proteins 9 and 15kDa are thought to be post translation modified versions of the 15kDa protein with a change in confirmation. Granulysin is found in NK and activated T cells and the expression is confined to the cytolytic granules which also contains perforin and granzyme. Granulysin with perforn are suspected to function synergistically to kill bacteria and induce apoptosis in nucleated cells. Applications Reported: This eBioDH2 (DH2) antibody has been reported for use in intracellular staining followed by flow cytometric analysis and immunocytochemistry. Applications Tested: This eBioDH2 (DH2) antibody has been pre-titrated and tested by intracellular staining and flow cytometric analysis of human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Antibody clone number
eBioDH2 (DH2)
Vial size
100 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
GNLY protein structure - 12-8828-42 shown in red.