Tissue expression
Cell line expression
Protein structure
GNLY
GranulysinD2S69E, LAG-2, LAG2, NKG5, TLA519
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies | 8 references | Monoclonal |
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| Novus Biologicals | Monoclonal |
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| antibodies-online | 2 references | Polyclonal |
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| BioLegend | 1 references | Monoclonal |
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| Proteintech Group | 1 references | Polyclonal |
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