Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ALX-804-355-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-355-C100, RRID:AB_2050934
- Product name
- Caspase-2 monoclonal antibody (10C6)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length protein
- Description
- Protein G-affinity purified.
- Reactivity
- Human, Mouse, Rat, Canine, Simian
- Host
- Rat
- Isotype
- IgG
- Antibody clone number
- 10C6
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death.
Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation.
Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9.
Marsden VS, Kaufmann T, O'reilly LA, Adams JM, Strasser A
Blood 2006 Mar 1;107(5):1872-7
Blood 2006 Mar 1;107(5):1872-7
Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation.
Scott CL, Schuler M, Marsden VS, Egle A, Pellegrini M, Nesic D, Gerondakis S, Nutt SL, Green DR, Strasser A
The Journal of cell biology 2004 Jan 5;164(1):89-96
The Journal of cell biology 2004 Jan 5;164(1):89-96
Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9.
O'Reilly LA, Ekert P, Harvey N, Marsden V, Cullen L, Vaux DL, Hacker G, Magnusson C, Pakusch M, Cecconi F, Kuida K, Strasser A, Huang DC, Kumar S
Cell death and differentiation 2002 Aug;9(8):832-41
Cell death and differentiation 2002 Aug;9(8):832-41
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