Tissue expression
Cell line expression
Protein structure
CASP2
Caspase 2ICH1, MGC2181, NEDD2, PPP1R57
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Top validated antibodies |
|||||
Biorbyt | orb1251428 | Monoclonal |
WB
EL
ICC
IP
IHC
IEM |
||
antibodies-online | ABIN2846317 | 3 references | Polyclonal |
WB
IHC
FC
|
|
Invitrogen Antibodies | MA5-31999 | Monoclonal |
WB
ICC
IHC
FC |
||
Enzo Life Sciences | ALX-804-356-C100 | 12 references | Monoclonal |
WB
ICC
IP
|
|
Novus Biologicals | NBP2-67333 | Monoclonal |
WB
ICC
IHC
FC |
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Enhanced validation
Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider