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Cell line expression
Protein structure
CHMP2B
Charged multivesicular body protein 2BCHMP2.5, DKFZP564O123, VPS2B
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-36184 |
Monoclonal |
WB
ICC
IP
IHC
FC
OA
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| Proteintech Group | 12527-1-AP |
13 references | Polyclonal |
WB
EL
ICC
IHC
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| LSBio | LS-C482436 |
Polyclonal |
WB
ICC
IHC
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| Biorbyt | orb866580 |
Monoclonal |
WB
ICC
IP
IHC
FC
|
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| NovoPro Bioscience Inc. | 109234 |
Polyclonal |
WB
EL
ICC
IHC
|
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