REXO2

This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]

Description

RNA exonuclease 2

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli, Focal adhesion sites, Mitochondria

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

11 (114439435 - 114450279)

Ensembl ID

ENSG00000076043  (ver. 103.38)

Orthologs

Mouse Rexo2: ENSMUSG00000032026

UniProt

Q9Y3B8

neXtProt

NX_Q9Y3B8

Human splice variants
Mouse splice variants

Protein structure