CABT-BL1297

antibody from Creative Diagnostics

Targeting: DMBT1 Gp-340, GP340, hensin, muclin, SALSA, vomeroglandin

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-BL1297

Provider

Creative Diagnostics

Product name

Anti-DMBT1 monoclonal antibody

Antibody type

Monoclonal

Description

Loss of sequences from human chromosome 10q has been associated with the progression of human cancers.The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line.DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized.The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID).Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition.This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Storage

Store in the dark at 4&deg