DPABH-09029

antibody from Creative Diagnostics

Targeting: NOTCH4 INT3

Western blot (Recommended by provider)

Antibody Data

Product number

DPABH-09029

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-09029, RRID:AB_2522850

Product name

Rabbit Anti-Human NOTCH4 Polyclonal Antibody

Antibody type

Polyclonal

Description

This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50ul, 100ul

Storage

Store at -20°C. Avoid freeze / thaw cycles.