Tissue expression
Cell line expression

NOTCH4

gene product
INT3 
This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Antigen sequence

Conjugate

Epitope

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
325 antibodies from 35 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
7 antibodies
antibodies-online
90 antibodies
NovoPro Bioscience Inc.
3 antibodies
R&D Systems
2 antibodies
GeneTex
4 antibodies
LifeSpan BioSciences, Inc.
92 antibodies
Cusabio Biotech Co., Ltd
3 antibodies
Aviva Systems Biology
4 antibodies
Biorbyt
19 antibodies
Invitrogen Antibodies
6 antibodies
Boster Biological Technology
3 antibodies
Cell Signaling Technology, Inc
1 antibody
HUABIO Research
1 antibody
Creative Diagnostics
6 antibodies
OriGene
5 antibodies
NSJ Bioreagents
2 antibodies
Abgent
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
RayBiotech, Inc.
1 antibody
Miltenyi Biotec
3 antibodies
Abbexa
5 antibodies
St John's Laboratory
3 antibodies
Creative Biolabs
23 antibodies
Leading Biology
4 antibodies
ProSci
2 antibodies
Abiocode, Inc.
1 antibody
MyBioSource
6 antibodies
RabMAbs
1 antibody
United States Biological
15 antibodies
EMD Millipore
2 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Everest Biotech
1 antibody
GenWay
1 antibody
Abnova Corporation
1 antibody