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Protein structure
KLK2
Kallikrein related peptidase 2This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
Top validated antibodies |
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| LSBio |  LS-C831515 |
Polyclonal |
WB
IHC
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| Proteintech Group | 10812-1-AP |
2 references | Polyclonal |
WB
EL
IHC
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| Novus Biologicals | NBP1-06046 |
1 references | Polyclonal |
WB
EL
IHC
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| R&D Systems | MAB4104 |
1 references | Monoclonal |
WB
IP
BN
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| Abnova Corporation | H00003817-M03 |
Monoclonal |
EL
ICC
IP
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