ABIN187469

antibody from antibodies-online

Targeting: MGMT

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN187469

Provider

antibodies-online

Product name

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 8-221) antibody

Antibody type

Monoclonal

Antigen

Purified recombinant human MGMT protein.

Reactivity

Human

Host

Mouse

Epitope

AA 8-221

Isotype

IgG

Antibody clone number

MT3-1

Vial size

100 μg

Storage

4°C

References

Submitted references

Bifunctional DNA alkylator 1,3-bis(2-chloroethyl)-1-nitrosourea activates the ATR-Chk1 pathway independently of the mismatch repair pathway.

Cui B, Johnson SP, Bullock N, Ali-Osman F, Bigner DD, Friedman HS
Molecular pharmacology 2009 Jun;75(6):1356-63

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Phase II study of extended-dose temozolomide in patients with melanoma.

Rietschel P, Wolchok JD, Krown S, Gerst S, Jungbluth AA, Busam K, Smith K, Orlow I, Panageas K, Chapman PB
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 May 10;26(14):2299-304

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Bone marrow-derived cells exhibiting lung epithelial cell characteristics are enriched in vivo using methylguanine DNA methyltransferase-mediated drug resistance.

Reese JS, Roth JC, Gerson SL
Stem cells (Dayton, Ohio) 2008 Mar;26(3):675-81