Tissue expression
Cell line expression
Protein structure
MGMT
O-6-methylguanine-DNA methyltransferaseAlkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]
Top validated antibodies |
|||||
Invitrogen Antibodies | MA3-16537 | 11 references | Monoclonal |
WB
ICC
IHC
FC
OA
|
|
antibodies-online | ABIN151202 | 20 references | Monoclonal |
WB
ICC
IHC
FC |
|
Novus Biologicals | NB100-168 | 16 references | Monoclonal |
WB
ICC
IHC
FC |
|
Proteintech Group | 17195-1-AP | 9 references | Polyclonal |
WB
EL
IP
IHC |
|
GeneTex | GTX27045 | 2 references | Monoclonal |
WB
ICC
IHC
FC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider