PLK3

gene product
CNK, FNK, PRK
The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis. [provided by RefSeq, Sep 2015]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
257 antibodies from 31 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
6 antibodies
Atlas Antibodies
1 antibody
antibodies-online
110 antibodies
NovoPro Bioscience Inc.
4 antibodies
LifeSpan BioSciences, Inc.
45 antibodies
Affinity Biosciences
1 antibody
Antibodies.com
1 antibody
NSJ Bioreagents
1 antibody
Proteintech Group
1 antibody
Biorbyt
14 antibodies
Abnova Corporation
4 antibodies
Abgent
3 antibodies
Invitrogen Antibodies
4 antibodies
GeneTex
3 antibodies
St John's Laboratory
3 antibodies
ProSci
2 antibodies
Cell Signaling Technology, Inc
1 antibody
Aviva Systems Biology
3 antibodies
Acris Antibodies GmbH
3 antibodies
Everest Biotech
1 antibody
OriGene
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
R&D Systems
1 antibody
Creative Biolabs
5 antibodies
MyBioSource
5 antibodies
Boster Biological Technology
1 antibody
RabMAbs
1 antibody
United States Biological
21 antibodies
Creative Diagnostics
4 antibodies
Sigma-Aldrich
2 antibodies
EMD Millipore
1 antibody