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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Product number
- ABIN362470 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cyclin E1 (CCNE1) (pThr395) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pThr395 (L-L-T (p) -P-P) derived from Human Cyclin E1 Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pThr395
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation.
Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E.
Welcker M, Singer J, Loeb KR, Grim J, Bloecher A, Gurien-West M, Clurman BE, Roberts JM
Molecular cell 2003 Aug;12(2):381-92
Molecular cell 2003 Aug;12(2):381-92
Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E.
Won KA, Reed SI
The EMBO journal 1996 Aug 15;15(16):4182-93
The EMBO journal 1996 Aug 15;15(16):4182-93
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