SLC15A2

The mammalian kidney expresses a proton-coupled peptide transporter that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate. This transporter, SLC15A2, belongs to the same gene family as SLC15A1 (MIM 600544), the proton-coupled peptide transporter found in the small intestine (Liu et al, 1995 [PubMed 7756356]). [supplied by OMIM, Feb 2011]

Description

Solute carrier family 15 member 2

Tissue specificity

Tissue enhanced (cervix, epididymis, prostate)

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters

Chromosome

3 (121894401 - 121944188)

Ensembl ID

ENSG00000163406  (ver. 103.38)

Orthologs

Mouse Slc15a2: ENSMUSG00000022899

UniProt

Q16348

neXtProt

NX_Q16348

Human splice variants
Mouse splice variants

Protein structure