Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B9426 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human FASTK monoclonal antibody, clone 3C8
- Antibody type
- Monoclonal
- Description
- The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
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