Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN258396 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Insulin Induced Gene 1 (INSIG1) (AA 1-100) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Rat
- Host
- Rabbit
- Epitope
- AA 1-100
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Analysis of the protein network of cholesterol homeostasis in different brain regions: an age and sex dependent perspective.
Regulation of cholesterol biosynthetic pathway in different regions of the rat central nervous system.
Short- and long-term regulation of 3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin.
Sex differences in hepatic regulation of cholesterol homeostasis.
Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake.
Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.
Segatto M, Di Giovanni A, Marino M, Pallottini V
Journal of cellular physiology 2013 Jul;228(7):1561-7
Journal of cellular physiology 2013 Jul;228(7):1561-7
Regulation of cholesterol biosynthetic pathway in different regions of the rat central nervous system.
Segatto M, Trapani L, Lecis C, Pallottini V
Acta physiologica (Oxford, England) 2012 Sep;206(1):62-71
Acta physiologica (Oxford, England) 2012 Sep;206(1):62-71
Short- and long-term regulation of 3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin.
Trapani L, Segatto M, Simeoni V, Balducci V, Dhawan A, Parmar VS, Prasad AK, Saso L, Incerpi S, Pallottini V
Biochimie 2011 Jul;93(7):1165-71
Biochimie 2011 Jul;93(7):1165-71
Sex differences in hepatic regulation of cholesterol homeostasis.
De Marinis E, Martini C, Trentalance A, Pallottini V
The Journal of endocrinology 2008 Sep;198(3):635-43
The Journal of endocrinology 2008 Sep;198(3):635-43
Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake.
Gong Y, Lee JN, Lee PC, Goldstein JL, Brown MS, Ye J
Cell metabolism 2006 Jan;3(1):15-24
Cell metabolism 2006 Jan;3(1):15-24
Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.
Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS
The Journal of clinical investigation 2005 Sep;115(9):2489-98
The Journal of clinical investigation 2005 Sep;115(9):2489-98
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- WB