INSIG1

gene product
CL-6, MGC1405
Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2009]
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147 antibodies from 15 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
14 antibodies
antibodies-online
60 antibodies
Aviva Systems Biology
4 antibodies
Biorbyt
3 antibodies
Proteintech Group
1 antibody
Invitrogen Antibodies
3 antibodies
GeneTex
5 antibodies
NovoPro Bioscience Inc.
2 antibodies
Abgent
1 antibody
LifeSpan BioSciences, Inc.
44 antibodies
OriGene
5 antibodies
Abnova Corporation
1 antibody
ProSci
1 antibody
MyBioSource
1 antibody
Sigma-Aldrich
2 antibodies