RA0543

antibody from Oursmab

Targeting: PCSK9 FH3, HCHOLA3, NARC-1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0543

Provider

Oursmab

Product name

Alirocumab (Biosimilar Reference Antibody) (PCSK9)

Antibody type

Monoclonal

Description

Alirocumab is a fully human monoclonal antibody (IgG1) designed as a PCSK9 inhibitor for the treatment of hypercholesterolemia. It functions by binding to and inhibiting circulating proprotein convertase subtilisin/kexin type 9, thereby preventing the degradation of hepatic LDL receptors. This leads to a sustained and significant reduction in low-density lipoprotein cholesterol levels. It is administered via subcutaneous injection and is approved for use in patients with atherosclerotic cardiovascular disease (ASCVD) or familial hypercholesterolemia (FH) who require additional LDL-C lowering despite maximally tolerated statin therapy, helping to reduce the risk of heart attack and stroke.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.