PCSK9

gene product
FH3, HCHOLA3, NARC-1
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
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698 antibodies from 39 providers.

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Novus Biologicals
55 antibodies
antibodies-online
148 antibodies
R&D Systems
7 antibodies
Proteintech Group
1 antibody
Invitrogen Antibodies
15 antibodies
Aviva Systems Biology
5 antibodies
Biorbyt
33 antibodies
GeneTex
6 antibodies
NovoPro Bioscience Inc.
18 antibodies
NSJ Bioreagents
7 antibodies
OriGene
18 antibodies
Abnova Corporation
7 antibodies
Abgent
7 antibodies
Arigo
2 antibodies
ProSci
5 antibodies
St John's Laboratory
5 antibodies
Everest Biotech
3 antibodies
LifeSpan BioSciences, Inc.
107 antibodies
Acris Antibodies GmbH
8 antibodies
Antibodies.com
3 antibodies
Boster Biological Technology
2 antibodies
Cell Signaling Technology, Inc
2 antibodies
RabMAbs
2 antibodies
Creative Biolabs
101 antibodies
MyBioSource
8 antibodies
United States Biological
68 antibodies
FabGennix
3 antibodies
Leading Biology
9 antibodies
Creative Diagnostics
4 antibodies
BioLegend
2 antibodies
Sino Biological Inc.
11 antibodies
Abiocode, Inc.
1 antibody
Affinity Biosciences
1 antibody
Bethyl Laboratories
1 antibody
Exalpha Biologicals, Inc.
4 antibodies
RayBiotech, Inc.
1 antibody
EMD Millipore
2 antibodies
Sigma-Aldrich
1 antibody