CYP2J2

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016]

Description

Cytochrome P450 family 2 subfamily J member 2

Tissue specificity

Group enriched (heart muscle, intestine, liver)

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (59893308 - 59926773)

Ensembl ID

ENSG00000134716  (ver. 103.38)

Orthologs

-

UniProt

P51589

neXtProt

NX_P51589

Human splice variants

Protein structure