Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- GTX70236 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX70236, RRID:AB_372873
- Product name
- RbAp48 + RbAp46 antibody [15G12]
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse
- Host
- Mouse
- Antibody clone number
- 15G12
- Storage
- Keep as concentrated solution. Store at 4¢XC short term. For extended storage aliquot and store at -20¢XC or below. Avoid freeze-thaw cycles.
Submitted references A phosphomimetic mutation in the Sall1 repression motif disrupts recruitment of the nucleosome remodeling and deacetylase complex and repression of Gbx2.
A conserved 12-amino acid motif in Sall1 recruits the nucleosome remodeling and deacetylase corepressor complex.
Murine Sall1 represses transcription by recruiting a histone deacetylase complex.
Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1.
RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.
An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells.
Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB.
Tissue-specific and developmental stage-specific DNA binding by a mammalian SWI/SNF complex associated with human fetal-to-adult globin gene switching.
BRCA1 interacts with components of the histone deacetylase complex.
Lauberth SM, Bilyeu AC, Firulli BA, Kroll KL, Rauchman M
The Journal of biological chemistry 2007 Nov 30;282(48):34858-68
The Journal of biological chemistry 2007 Nov 30;282(48):34858-68
A conserved 12-amino acid motif in Sall1 recruits the nucleosome remodeling and deacetylase corepressor complex.
Lauberth SM, Rauchman M
The Journal of biological chemistry 2006 Aug 18;281(33):23922-31
The Journal of biological chemistry 2006 Aug 18;281(33):23922-31
Murine Sall1 represses transcription by recruiting a histone deacetylase complex.
Kiefer SM, McDill BW, Yang J, Rauchman M
The Journal of biological chemistry 2002 Apr 26;277(17):14869-76
The Journal of biological chemistry 2002 Apr 26;277(17):14869-76
Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1.
Humphrey GW, Wang Y, Russanova VR, Hirai T, Qin J, Nakatani Y, Howard BH
The Journal of biological chemistry 2001 Mar 2;276(9):6817-24
The Journal of biological chemistry 2001 Mar 2;276(9):6817-24
RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.
Lai A, Kennedy BK, Barbie DA, Bertos NR, Yang XJ, Theberge MC, Tsai SC, Seto E, Zhang Y, Kuzmichev A, Lane WS, Reinberg D, Harlow E, Branton PE
Molecular and cellular biology 2001 Apr;21(8):2918-32
Molecular and cellular biology 2001 Apr;21(8):2918-32
An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells.
O'Neill DW, Schoetz SS, Lopez RA, Castle M, Rabinowitz L, Shor E, Krawchuk D, Goll MG, Renz M, Seelig HP, Han S, Seong RH, Park SD, Agalioti T, Munshi N, Thanos D, Erdjument-Bromage H, Tempst P, Bank A
Molecular and cellular biology 2000 Oct;20(20):7572-82
Molecular and cellular biology 2000 Oct;20(20):7572-82
Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB.
Zhang Q, Vo N, Goodman RH
Molecular and cellular biology 2000 Jul;20(14):4970-8
Molecular and cellular biology 2000 Jul;20(14):4970-8
Tissue-specific and developmental stage-specific DNA binding by a mammalian SWI/SNF complex associated with human fetal-to-adult globin gene switching.
O'Neill D, Yang J, Erdjument-Bromage H, Bornschlegel K, Tempst P, Bank A
Proceedings of the National Academy of Sciences of the United States of America 1999 Jan 19;96(2):349-54
Proceedings of the National Academy of Sciences of the United States of America 1999 Jan 19;96(2):349-54
BRCA1 interacts with components of the histone deacetylase complex.
Yarden RI, Brody LC
Proceedings of the National Academy of Sciences of the United States of America 1999 Apr 27;96(9):4983-8
Proceedings of the National Academy of Sciences of the United States of America 1999 Apr 27;96(9):4983-8
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 μg of whole cell lysate) A: Raji B: K562 C: THP-1 D: HL-60 10% SDS PAGE GTX70236 diluted at 1:1000
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using RbAp48 + RbAp46(GTX70236) antibody at 1:200 dilution.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded C2C12 xenograft, using RbAp48 + RbAp46(GTX70236) antibody at 1:200 dilution.