Tissue expression
Cell line expression
Protein structure
RBBP4
RB binding protein 4, chromatin remodeling factorlin-53, NURF55, RbAp48
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Top validated antibodies |
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GeneTex | GTX70232 | 10 references | Monoclonal |
WB
ICC
IP
IHC
BN
FA
ChIP
|
|
Novus Biologicals | NB500-123 | 8 references | Monoclonal |
WB
ICC
IP
IHC
BN
FA
ChIP
|
|
Invitrogen Antibodies | MA1-23275 | 3 references | Monoclonal |
WB
ICC
IP
IHC
ChIP
OA |
|
antibodies-online | ABIN152949 | 4 references | Monoclonal |
WB
ICC
IP
IHC
BN
FA
ChIP
|
|
Proteintech Group | 20364-1-AP | 5 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider