Tissue expression
Cell line expression
Protein structure
DYNLT1
Dynein light chain Tctex-type 1TCTEL1
This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Top validated antibodies |
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Proteintech Group | 11954-1-AP | 9 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 11954-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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Boster Biological Technology | A05556 | Polyclonal |
WB
EL
ICC
IHC
FC
|
||
Biorbyt | orb402563 | Polyclonal |
WB
EL
ICC
IHC
FC
|
||
NovoPro Bioscience Inc. | 110142 | Polyclonal |
WB
EL
IP
IHC |
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