abx003064

antibody from Abbexa

Targeting: DYNLT1 TCTEL1

Western blot (Recommended by provider)

Antibody Data

Product number

abx003064

Provider

Abbexa

Product name

Dynein Light Chain Tctex-Type 1 (DYNLT1) Antibody

Antibody type

Polyclonal

Description

DYNLT1 Antibody is a Rabbit Polyclonal antibody against DYNLT1. This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

> 1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.